Down Syndrome Essay Sample

Familial factors are the exclusive cause of some non-infectious diseases ; such familial diseases are inherited or are caused by errors during cell division when gametes are formed ( Alters. 2005 ) . Down syndrome is caused by mistakes during the gamete formation.

Superimposed upon his single features. each kid and grownup with Down syndrome has characteristics that he portions with others who have Down syndrome ( Selikowitz. 1997 ) . Down syndrome comes approximately when there is an excess figure 21 chromosome. this extra chromosome. because of the cistron it contains. causes an inordinate sum of certain proteins to be formed in the cell which in return disturbs normal growing in the organic structure of the foetus ( Selikowitz. 1997 ) . ‘Chromosome 21’ is the tinniest of the all the human-chromosomes and have about 225 cistrons. Harmonizing to statistics. 95 % of kids with Down syndrome have ‘trisonomy 21’ or an extra chromosome in all their cells. 3-4 % have translocation-form of the extra chromosome where the extra-chromosome 21 is connected to one of the different chromosome-pair and around 1-2 % of kids have mosaic signifier in which merely some cells are trisonomic while the others are normal.

Harmonizing to Selikowitz. as the foetus develops. the cells of the organic structure do non split every bit quickly as they usually do. and this consequence in fewer organic structure cells. and. therefore a smaller babe. The babe. holding fewer encephalon cells and a different encephalon formation. will larn easy.

A strong statement for the familial preparation of Alzheimer’s disease stems from its connexion with Down syndrome. An excess chromosome 21 exist in individuals with Down syndrome ; non merely do people with Down syndrome begin to develop symptoms of dementedness after the age 35. but besides the prevalence of Alzheimer’s disease is higher in households with Down syndrome. and frailty versa ( Eliopoulos. 2004 ) . An altered chromosome 21 causes an unnatural amyloid to be produced.

Mentions

Alters. S. ( 2005 ) .Essential Concepts for Healthy Living. New York: Jones & A ; Bartlett Publishers.

Eliopoulos. C. ( 2004 ) .Gerontology Nursing. New York: Lippincott Williams & A ; Wilkins.

Selikowitz. M ( 1997 ) .Down Syndrome: The Facts. New York: Ovford University Press.