Rho(D) Immune Globulin (RhoGAM) Essay Sample

A female parent who is 24 hours postpartum and blood type A Rh-negative is to be given RhoGAM. She tells the nurse that she was already given the RhoGAM when she was pregnant. and wants to cognize why she needs it once more. How does the nurse explain the ground for necessitating it now and what process needs to be followed anterior to the disposal of the medicine? The new female parent demands to be advised that it is protocol to be administered RhoGAM if she is Rh-negative and is found non to be sensitized to anti-D antibodies ( via indirect Coombs’ trial ) . The RhoGAM “dosage depends on gestation: 50 microgram ( microdose ) of D Ig is administered before 13 gestational hebdomads and 300 microgram is given thenceforth ( as prophylaxis ) . During the postnatal period. D immune globulin should be administered within 72 hours” ( Kee. Hayes. McCuistion. 2009. p. 867 ) . The nurse can explicate in layman’s footings what may go on when an Rh-negative adult female bears an Rh-positive kid for the first clip.

She will be told that her organic structure will bring forth anti-D “antibodies against incompatible Rh-positive blood” ( Kee. et. Al. . 2009. p. 866 ) and “in subsequently exposure. as with subsequent gestations. there is a more rapid IgG ( secondary ) immune response and increased potency for foetal haemolysis ( rupture or devastation of ruddy blood cells ) in an Rh-positive fetus” ( Kee. et. Al. . 2009. p. 866 ) . In order to protect the viability of future foetuss. she must be given “a unfertile concentrated solution of gamma globulin prepared from human serum incorporating antibodies to the Rh factor ( D antigen ) . besides expressed as anti-Rho ( D ) ( Kee. et. Al. . 2009. p. 867 ) . Prior to giving the initial RhoGAM injection ( or infrequently as IV disposal ) . the woman’s blood type and Rh position must be determined. The nurse must so measure the woman’s apprehension of her and baby’s father’s Rh position. every bit good as happening out if the adult female has had anterior gestations and their result ; and besides if she has of all time received RhoGAM in the yesteryear. The health care squad must follow bureau protocol for Rh blood proving for the female parent to be and pamper at clip of bringing. and besides must happen out if the adult female has a history of allergic reaction to immune globulin merchandises.

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It is besides of import to happen out about the client’s spiritual beliefs because some households may see it a blood merchandise. The nurse must besides be diligent in acquiring written consent before disposal. If they refuse. they must subscribe a refusal signifier ( drug declined ) .


Kee. J. L. . Hayes. E. R. . & A ; McCuistion. L. E. ( 2009 ) . Pharmacology A Nursing Procedure

Approach. St. Louis. Moment: Saunders Elsevier