Tabernaemontana Pandacaqui Poir Essay Sample

A. Background of the Study
One of the more common happenings in our day-to-day life is prolonging lesions runing from mild scratchs to deep lacerations. Wounds that are left untreated can ensue to infections and other complications. so proper redress must be done instantly.

For the past several old ages. there has been a batch of promotion in the field of medical specialty. The find of new drugs has played a large function in the betterment of our wellness attention. But due to the prohibitory cost of these drugs. people tend to utilize herbs as an option.

Surveies have shown that some workss are every bit effectual as the drugs found in the apothecary’s shops. There are workss found in the Philippines that have different utilizations such as in the intervention of diseases and unwellnesss. Examples of these workss are guava. lagundi and marjoram. Boiled Psidium littorale foliages are used as a germicide to handle lesions. lagundi foliages are used to handle cough and the decoction of the marjoram foliages are used to bring around tummy achings and degenerative arthritis. Their healing and medicative belongingss can function as an option to pharmaceutical drugs which could be expensive. These medicative workss came from natural beginnings. doing them even more good because of their cost-effectiveness.

Pandakaki-puti is a bush with extended foliages and white flowers. Its foliages can be used as an analgetic. anti-inflammatory. and intervention for hypotention. Besides these. the white milky sap from the foliage of the pandakaki-puti ( Tabernaemontana pandacaqui Poir ) has been used for alleviating antsy skin lesions and eczema. This survey aims to find the effectivity of the sap of the pandakaki-puti foliages. when made into an unction. on the lesion healing of the rat. B. Aim

The aims of this survey is o determine the effectivity of the pandakaki-puti unction on the lesion healing of the rat and to compare the mending rates of the lesion that is treated with the pandakaki-puti unction with that of the control. C. Significance of the Study

This research explores the kingdom of alternate medical specialty with our local workss as its beginning. Medicines are going more & A ; more unaffordable due to its intensifying cost. Cheaper options that are every bit effectual like Tabernaemontana Pandacaqui Poir will be preferred by the marginalized sector. This works can be found in 1s backyard. doing it readily available. Friendliness to the environment is besides one factor to be considered. Manufacturing. packaging & A ; importation of the drugs by the pharmaceutical company will necessarily do some chemical pollution that would destruct mother Earth.

In handling lesions. the faster the healing clip the better. A natural manner is by utilizing the sap of pandakaki-puti foliages. Determining its rate of lesion healing will enable us to cut down morbidity the soonest possible clip. D. Scope

The coverage of this survey is to find the effectivity of the sap of the pandakaki-puti foliages. when made into an unction. on the lesion healing of the rat and to compare the mending rates between the lesion that is treated with the unction and the untreated lesion. However. this survey will non be comparing the effectivity of the pandakaki-puti unction with other works merchandises.

II. Review of Related Literature

To bring around eczema. furuncle 3 cups of shredded foliages in one gallon of H2O for 10 proceedingss ; add 2 gallons of hot H2O. Besides. fry the fresh foliages in oil and use to itchy teguments lesions for diagnostic alleviation.

Wound mending. or cicatrisation. is an intricate procedure in which the tegument ( or another organ-tissue ) repairs itself after hurt. In normal tegument. the cuticle ( outermost bed ) and corium ( inner or deeper bed ) exists in steady-state equilibrium. organizing a protective barrier against the external environment. Once the protective barrier is broken. the normal ( physiologic ) procedure of lesion healing is instantly set in gesture. The authoritative theoretical account of lesion healing is divided into three or four sequential. yet overlapping. stages: ( 1 ) haemostasis ( non considered a stage by some writers ) . ( 2 ) inflammatory. ( 3 ) proliferative and ( 4 ) remodeling. Upon hurt to the tegument. a set of complex biochemical events takes topographic point in a closely orchestrated cascade to mend the harm. Within proceedingss post-injury. thrombocytes ( platelets ) aggregate at the hurt site to organize a fibrin coagulum. This coagulum acts to command active hemorrhage ( haemostasis ) . In the inflammatory stage. bacteriums and dusts are phagocytosed and removed. and factors are released that cause the migration and division of cells involved in the proliferative stage. The proliferative stage is characterized by angiogenesis. collagen deposition. granulation tissue formation. epithelialization. and wound contraction.

In angiogenesis. new blood vass are formed by vascular endothelial cells. In fibroplasia and granulation tissue formation. fibroblasts grow and form a new. probationary extracellular matrix ( ECM ) by egesting collagen and fibronectin. Concurrently. re-epithelialization of the cuticle occurs. in which epithelial cells proliferate and ‘crawl’ atop the lesion bed. supplying screen for the new tissue. In contraction. the lesion is made smaller by the action of myofibroblasts. which set up a clasp on the lesion borders and contract themselves utilizing a mechanism similar to that in smooth musculus cells. When the cells’ functions are close to finish. unnecessary cells undergo programmed cell death. In the ripening and reconstructing stage. collagen is remodeled and realigned along tenseness lines and cells that are no longer needed are removed by programmed cell death. However. this procedure is non merely complex but delicate. and susceptible to break or failure taking to the formation of non-healing chronic lesions. Factors which may lend to this include diabetes. venous or arterial disease. old age. and infection.

III. Methodology
A. Materials
2 male albino rat
rat coop
nutrient and H2O for the rat
calliper
blade
sap of the pandakaki-puti foliage
little unction container
beeswax
vegetable oil
metal pan
chromium steel spoon
chromium steel bowl
H2O
razor
howitzer and stamp

B. Treatment/ General Procedure
To do the ointment base. 8 gms of vegetable oil and 8 gms of beeswax were placed in a chromium steel steel bowl and were heated in a H2O bath until they melted. Then. 8 gms of the sap of the pandakaki-puti foliage. which was extracted with the usage of a howitzer and stamp. was added to the mixture and was stirred good. The mixture was so removed from the H2O bath and it was transferred to an ointment container to chill.